ArticleJournal of pharmacy & bioallied sciences2026
Gold Nanoparticles and Chitosan Nanoparticles: A Systematic Review.
Article in Journal of pharmacy & bioallied sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Effect of chitosan and bioactive glass nanoparticles on pulp-dentin regeneration: a systematic review ofFrontiers in dental medicine · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gold nanoparticles (AuNPs) and chitosan nanoparticles (CNPs) have emerged as multifunctional nanomaterials in biomedical sciences, particularly in conservative and endodontic dentistry. Thei antimicrobial, biocompatible, and regenerative properties make them promising candidates for enhancing clinical outcomes. This systematic review aimed to evaluate and synthesize the current evidence on the application of AuNPs and CNPs in endodontics and conservative dentistry. A systematic literature search was performed using PubMed, Scopus, and Web of Science databases up to April 2025. Studies focusing on the synthesis, characterization, and dental application of AuNPs and/or CNPs were included. After applying Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, 10 studies were selected and analyzed qualitatively. Most studies demonstrated strong antimicrobial efficacy of chitosan-AuNP composites against biofilm-forming bacteria relevant to caries and endodontic infections. Some studies also highlighted enhanced sealing ability, siRNA delivery, drug release, and photothermal therapeutic applications. Several formulations showed high biocompatibility and regenerative potential. Gold and CNPs present significant promise in improving antimicrobial disinfection, restorative sealing, and regenerative outcomes in dentistry. However, further in vivo and clinical research is necessary to confirm their long-term safety and efficacy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.