Evidence map›Paper›PMID 41853008›Full record

ArticleJournal of pharmacy & bioallied sciences2026

Evaluating the Impact of Early Orthodontic Intervention on Pediatric Craniofacial Development: A Longitudinal Study.

Vijender Kumar, Danish U Z Khan, Shweta N Lakra, Lincy R Thomas, Mohit Zarekar, Najmul Huda, Miral Mehta

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vijender KumarDepartment of Orthodontics and Dentofacial Orthopedics, MM College of Dental Sciences and Research, Ambala, Haryana, India.
Danish U Z KhanDepartment of Dentistry, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
Shweta N LakraDepartment of Orthodontics and Dentofacial Orthopedics, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India.
Lincy R ThomasDepartment of Orthodontics, Faculty of Dentistry, AIMST University, Bedong, Kedah, Malaysia.
Mohit ZarekarDepartment of Pedodontics and Preventive Dentistry, Zarekar's Pediatric and Family Multi-Speciality Dental Clinic, Ahilyanagar, Maharashtra, India.
Najmul HudaDepartment of Orthodontics and Dentofacial Orthopedics, Infinite Smiles Multispecialty Dentistry, Hyderabad, Telangana, India.
Miral MehtaDepartment of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To compare the impact of early orthodontic treatment to an untreated control group in order to assess how it affects pediatric patients' craniofacial development and dental relationships. Methodology: Twelve children between the ages of 8 and 10 years participated in the intervention group and an untreated control group in this 36-month follow-up study. Both the baseline and final evaluations included thorough cephalometric, dental, and soft tissue evaluations. Result: Sagittal jaw relationships, maxillary transverse width, overjet and overbite reduction, facial convexity, and lip competence all significantly improved in the intervention group. There were not many changes in the control group. Significant intergroup differences were confirmed by statistical analysis ( Conclusion: By improving occlusal harmony, improving facial aesthetics, and positively influencing craniofacial growth, early orthodontic treatment during the mixed dentition stage may lessen the need for more involved future interventions.

Indexed as

Class II malocclusionearly orthodontic interventionfacial aestheticsfunctional appliancesmandibular growthocclusal harmonyorthopedic correctionpediatric craniofacial developmentskeletal discrepanciestwin-block appliancetwo-phase orthodontic treatment

Identifiers

PMID41853008
PMCPMC12995159

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.