Evidence map›Paper›PMID 41852920›Full record

ArticleIJID regions2026

Navigating Candidemia in a tertiary hospital: A 4-year epidemiologic and clinical review.

Chadi Hage Chehade, Bassem Habr, Carine Harmouche, May Fakhoury, Nabil Chehata, Hassan Choker, Christian Haddad, Issam Daou, Zeina Bou Chebl, Racha Eid and 1 more

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In one paragraph

Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chadi Hage ChehadeInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Bassem HabrPulmonary and Critical Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Carine HarmouchePulmonary and Critical Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
May FakhouryPharmacy Department, Hôtel-Dieu de France, Faculty of Pharmacy, Saint-Joseph University, Beirut, Lebanon.
Nabil ChehataInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Hassan ChokerInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Christian HaddadInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Issam DaouCardiology Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Zeina Bou CheblInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Racha EidClinical Microbiology Department, Hôtel-Dieu de France, Faculty of Pharmacy, Saint-Joseph University, Beirut, Lebanon.
Elie HaddadInfectious Diseases Department, Hôtel-Dieu de France, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study describes the epidemiology, risk factors, therapeutic management, antifungal resistance patterns, and clinical outcomes of candidemia in hospitalized patients. It also examines predictors of 30-day mortality and factors associated with Methods: A retrospective review was conducted at a tertiary care center in Lebanon (2017-2021). Clinical, microbiological, and treatment data were extracted from medical records. Statistical analyses were performed to identify factors associated with 30-day mortality and the occurrence of CA vs NCA species. Results: A total of 98 candidemia episodes in 93 patients were analyzed. CA and NCA species were equally represented (50% each). Resistance was highest to fluconazole and itraconazole (7.3%). The 30-day mortality rate was 38.8%. Factors significantly associated with increased mortality included intensive care unit admission (odds ratio [OR] 7.42), chronic renal failure (OR 7.29), dialysis (OR 7.28), mechanical ventilation (OR 4.71), and central venous catheters (OR 10.91). Catheter removal was protective (OR 0.205, Conclusion: Antifungal resistance remains relatively low in this cohort; however, candidemia continues to carry a high mortality rate. Optimizing management through adherence to international guidelines and specialist oversight is essential to improve outcomes and address the diverse clinical presentations of CA and NCA infections.

Indexed as

AntifungalCandida albicansCandidemiaNon-candida albicans

Identifiers

PMID41852920
PMCPMC12993881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.