Evidence map›Paper›PMID 41852886›Full record

ArticleMaterials today. Bio2026

Chitosan-based hydrogel facilitates DC-SIGN-mediated monocyte-to-dendritic cell transformation in vivo for antigen-specific antitumor therapy.

Jiake Lin, Benke Li, Xun Wang, Yuemin Zhou, Jinyuan Song, Jianghui Tang, Junlei Zhang, Haibin Hao, Yongtao Ji, Zhenyu Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jiake LinZhejiang University School of Medicine, Hangzhou, 310027, PR China.
Benke LiDepartment of Chemistry, Zhejiang University., Hangzhou, 310027, PR China.
Xun WangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Yuemin ZhouDepartment of Chemistry, Zhejiang University., Hangzhou, 310027, PR China.
Jinyuan SongZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Jianghui TangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Junlei ZhangZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Haibin HaoShandong Provincial Hospital Affiliated with Shandong First Medical University, Jinan, 250021, PR China.
Yongtao JiZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Zhenyu LiuDepartment of Chemistry, Zhejiang University., Hangzhou, 310027, PR China.
Xingcan ShenState Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Medicine School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin, 541004, PR China.
Xiao ChenZhejiang University School of Medicine, Hangzhou, 310027, PR China.
Jianpeng ShengZhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, PR China.
Ruikang TangLiangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, PR China.
Xiaoyu WangLiangzhu Laboratory, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo-generated monocyte-derived dendritic cells (moDCs) play a pivotal role in inducing effective immune responses against infections and cancer due to their exceptional cross-presentation capabilities. However, the in vivo generation of moDCs during immunotherapy is constrained by the absence of safe and efficient in vivo strategies. Here, we propose a chitosan oligosaccharide-based CaCO

Indexed as

Chitosan hydrogelDC-SIGNMonocyte-to-moDCs conversionPrimary liver cancer model

Identifiers

PMID41852886
PMCPMC12992966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.