Evidence map›Paper›PMID 41852794›Full record

ReviewJournal of clinical orthopaedics and trauma2026

Staged conversion after circular ring external fixation in adult open long-bone fractures: A systematic review.

Domenico Fenga, Daniel Pérez-Prieto, Gabriele Giuca, Paolo Rizzo, Biagio Zampogna, Danilo Leonetti

Abstract readReview
In one paragraph

Review in Journal of clinical orthopaedics and trauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Domenico FengaSection of Orthopaedics and Traumatology, Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, 98122, Messina, ME, Italy.
Daniel Pérez-PrietoHospital del Mar, Barcelona, Spain, Autonomous University of Barcelona, Barcelona, Spain.
Gabriele GiucaSection of Orthopaedics and Traumatology, Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, 98122, Messina, ME, Italy.
Paolo RizzoSection of Orthopaedics and Traumatology, Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, 98122, Messina, ME, Italy.
Biagio ZampognaSection of Orthopaedics and Traumatology, Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, 98122, Messina, ME, Italy.
Danilo LeonettiSection of Orthopaedics and Traumatology, Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, 98122, Messina, ME, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Circular ring external fixation is frequently used in high-energy open long-bone fractures, yet prolonged frame retention is associated with pin-tract morbidity and patient burden. Staged conversion to internal fixation is therefore attractive, but concerns persist regarding deep infection and nonunion. We systematically reviewed the evidence on outcomes and timing of staged conversion following circular ring fixation in adult open long-bone fractures. Methods: This review followed PRISMA 2020 guidelines and was registered in PROSPERO (CRD42021023282). PubMed, Embase, Cochrane Library, and Scopus were searched from inception to December 2025. We included studies of adult open long-bone fractures managed with circular ring external fixation, comparing definitive ring fixation versus staged conversion to internal fixation or reporting outcomes after conversion. Owing to clinical and methodological heterogeneity, a narrative synthesis was performed. Primary outcomes were reported deep infectious complications (including fracture-related infection when explicitly defined) and union. Results: Eight studies (303 patients) were included; however, only six acute traumatic open-fracture cohorts contributed to the primary synthesis, while two reconstructive/infected nonunion series were considered contextual only. Across the limited acute-trauma data, staged conversion was associated with fewer frame-related complications in some cohorts, but any effect on deep infectious complications and union remained uncertain because of inconsistent definitions, small sample sizes, and confounding by indication. Conclusions: The current evidence base is dominated by small, retrospective and methodologically heterogeneous studies. In acute traumatic open long-bone fractures treated with circular ring fixation, staged conversion after soft-tissue stabilization may reduce frame-related morbidity but whether it influences deep infection or union remains uncertain. Present data should therefore be interpreted as low-certainty observations rather than reliable comparative evidence. Level of evidence: Level IV.

Indexed as

External ring fixatorFracture healingGustilo-anderson classificationIlizarovInternal fixationOpen fracturesPin tract infection

Identifiers

PMID41852794
PMCPMC12993332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.