Evidence map›Paper›PMID 41852673›Full record

ArticleAnnals of intensive care2026

Impact of PEEP on V/Q mismatch according to patient position and recruitability: a clinical prospective study.

Zhiqian Zha, Zhichang Wang, Qiyu Cheng, Shanshan Meng, Jingyuan Xu, Jianfeng Xie, Haibo Qiu, Yi Yang, Fengmei Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of intensive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiqian ZhaJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Zhichang WangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Qiyu ChengJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Shanshan MengJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Jingyuan XuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Jianfeng XieJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Haibo QiuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Yi YangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Fengmei GuoJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High positive end-expiratory pressure (PEEP) may improve ventilation-perfusion (V/Q) mismatch in acute respiratory distress syndrome (ARDS) patients with high recruitability in supine position. However, impacts of PEEP on V/Q mismatch in prone position relative to supine position remain poorly understood. We aimed to compare PEEP effects between positions, and evaluate its relationship with lung recruitability. Methods: A total of 50 patients with moderate-to-severe ARDS were consecutively enrolled. Recruitment-to-inflation (R/I) ratio was used to measure baseline lung recruitability. V/Q mismatch, gas exchange, and respiratory mechanics were evaluated at PEEP 5 cm H Results: Median R/I ratio was 0.60 [0.38, 0.72], separating patients with higher and lower R/I ratio. In patients with higher R/I ratio, PEEP 15 cm H Conclusions: In patients with higher R/I ratio, PEEP 15 cm H

Indexed as

Acute respiratory distress syndromeElectrical impedance tomographyPositive end-expiratory pressureVentilation/perfusion mismatch

Identifiers

PMID41852673
PMCPMC12993242

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.