Evidence map›Paper›PMID 41852636›Full record

ArticleACS pharmacology & translational science2026

Effect of a Negatively Charged Amino Acid Linker on the Tumor-Targeting Properties of [

Zheng Qiao, Jingli Xu, Fabio Gallazzi, Jing Wang, Charles J Smith, Yubin Miao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS pharmacology & translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zheng QiaoDepartment of Radiology, University of Colorado Denver, Aurora, Colorado 80045, United States.
Jingli XuDepartment of Radiology, University of Colorado Denver, Aurora, Colorado 80045, United States.
Fabio GallazziDepartment of Chemistry and Molecular Interactions Core, University of Missouri, Columbia, Missouri 65211, United States.
Jing WangDepartment of Radiology and Stony Brook Cancer Center, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York 11794, United States.
Charles J SmithResearch Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, Missouri 65201, United States.ORCID https://orcid.org/0000-0001-7330-4185
Yubin MiaoDepartment of Radiology, University of Colorado Denver, Aurora, Colorado 80045, United States.ORCID https://orcid.org/0000-0002-6607-4403

Funding

Novel Receptor-Targeting Peptides for Melanoma TherapyR01CA225837 · NCI · UNIVERSITY OF COLORADO DENVER · PI MIAO, YUBIN · 2018 to 2022
$1.9M
Combinations of Receptor-Targeted Alpha Radionuclide Therapy and Immune Checkpoint Inhibitors for Melanoma TreatmentR01CA269221 · NCI · UNIVERSITY OF COLORADO DENVER · PI MIAO, YUBIN · 2023 to 2025
$1.8M
BLRD VA IK6 BX006810NCI NIH HHS R01 CA225837NCI NIH HHS R01 CA269221
6 · The paper itself

Abstract

This study aimed to examine how negatively charged amino acid linkers influence the tumor-targeting and biodistribution properties of [

Indexed as

4-p-(tolyl)butyric acidalbumin binderalpha-melanocyte-stimulating hormoneamino acid linkermelanocortin-1 receptormelanoma targeting

Identifiers

PMID41852636
PMCPMC12993784

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.