Evidence map›Paper›PMID 41852451›Full record

ArticleRegenerative therapy2026

Advances in In Vitro Vascularization of Engineered Tissues: From Microvessel Formation to Hepatic Tissue Integration.

Yen-Hsiang Huang, Akira Ono, Ryo Sudo

Abstract read
In one paragraph

Article in Regenerative therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yen-Hsiang HuangSchool of Integrated Design Engineering, Graduate School of Science and Technology, Keio University, Japan.
Akira OnoSchool of Integrated Design Engineering, Graduate School of Science and Technology, Keio University, Japan.
Ryo SudoSchool of Integrated Design Engineering, Graduate School of Science and Technology, Keio University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in tissue engineering have enabled the construction of two-dimensional tissues such as skin and cornea, as well as avascular three-dimensional (3D) tissues such as cartilage. However, building fully functional 3D tissues and organs remains a major challenge. In 3D constructs, microvascular networks are indispensable for delivering oxygen and nutrients to the inner regions; thus, the formation of capillaries and microvessels and their integration with 3D parenchymal tissues--so-called vascularization--are of critical importance. In this review, we discuss the current status and future perspectives of

Indexed as

CapillaryLiverMicrofluidic platformMicrovesselMultiphoton lithographyTissue engineeringVascularization

Identifiers

PMID41852451
PMCPMC12992525

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.