Evidence map›Paper›PMID 41852391›Full record

ReviewFrontiers in microbiomes2025

Understanding the role of oral and vaginal microbiomes in HPV-related cervical, head, and neck cancers: knowledge gaps and feasibility in Sub-Saharan Africa.

Hélène Eya Kamassa, Gnatoulma Katawa, Abiola Isawumi, Charles Olwal, Winfried Seth Gbewonyo, Peter Kojo Quashie, Yaw Bediako

Abstract readReview
In one paragraph

Review in Frontiers in microbiomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hélène Eya KamassaWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Gnatoulma KatawaLaboratoire de Microbiologie et de Contrôle de Qualité des Denrées Alimentaires, Unité de Recherche en Immunologie et Immunomodulation (UR2IM), Ecole Supérieure des Techniques Biologiques et Alimentaires (ESTBA), Université de Lomé, Lomé, Togo.
Abiola IsawumiWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Charles OlwalWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Winfried Seth GbewonyoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Peter Kojo QuashieWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.
Yaw BediakoWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbiome dysbiosis, characterized by an imbalance in the composition of microbial communities, has emerged as a potential risk factor for the development of cervical, head, and neck cancers. While previous studies have predominantly focused on high-income countries, there is a significant gap in understanding the relationship between microbiome alterations and cancer development in sub-Saharan Africa. Considering the unique socio-economic and environmental factors in this region, investigating the role of vaginal and oral microbiota in the progression of these cancers is crucial. This review explores the involvement of microbial dysbiosis in cervical, head, and neck cancers, particularly how it influences Human Papillomavirus-driven immune evasion, and highlights the importance of microbiota profiling in sub-Saharan Africa. The implications of these insights for cancer prevention and treatment strategies in this population are also discussed.

Indexed as

cervical/head and neck cancersHPVimmune evasionmicrobiome dysbiosisoral microbiotasub-Saharan Africavaginal microbiota

Identifiers

PMID41852391
PMCPMC12993497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.