Evidence map›Paper›PMID 41852366›Full record

ArticleJHLT open2026

Differential hypercapnia: Recognition, management, and outcomes in an awake patient supported with peripheral veno-arterial extracorporeal membrane oxygenation.

Terrance Oster, Casey Miller, Melissa Morris, Sarah Ruhland, C Christopher Zalesky, Sagar B Dave

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Terrance OsterDivision of Cardiothoracic Surgery, Department of Surgery, Emory Healthcare, 1364 Clifton Rd. NE, Atlanta, GA.
Casey MillerDivision of Cardiothoracic Surgery, Department of Surgery, Emory Healthcare, 1364 Clifton Rd. NE, Atlanta, GA.
Melissa MorrisDivision of Cardiothoracic Surgery, Department of Surgery, Emory Healthcare, 1364 Clifton Rd. NE, Atlanta, GA.
Sarah RuhlandDivision of Cardiothoracic Surgery, Department of Surgery, Emory Healthcare, 1364 Clifton Rd. NE, Atlanta, GA.
C Christopher ZaleskyDepartment of Anesthesiology, Emory University School of Medicine, 1364 Clifton Rd. NE, Atlanta, GA.
Sagar B DaveDepartment of Anesthesiology, Emory University School of Medicine, 1364 Clifton Rd. NE, Atlanta, GA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving intervention for individuals with refractory cardiopulmonary failure and is associated with several complications. Differential hypercapnia, also known as RIDDLER syndrome or East-West Syndrome, is a complication, at times exacerbated iatrogenically, where competitive flow dynamics lead to relative increase in carbon dioxide delivery from the descending aorta in awake patients supported with peripheral VA-ECMO. This case report presents the clinical course, diagnostic features, management, and outcome for a patient who developed differential hypercapnia during awake peripheral VA-ECMO cannulation and support.

Indexed as

DeliriumDifferential CO2 clearanceDifferential hypercapniaEast-West syndromePeripheral VA-ECMORIDDLER syndromeVeno-arterial ECMO

Identifiers

PMID41852366
PMCPMC12993875

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.