Evidence map›Paper›PMID 41852281›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

An ATP-Mediated Antibiotic β-Peptide Nanofiber That Kills Multidrug-Resistant Bacteria via a Multistage Mechanism.

Sohini Chakraborty, Kamal El Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs Szigyártó, Loránd Románszki and 12 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Sohini ChakrabortyInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Kamal El BattiouiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Dániel MolnárInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Bálint JezsóInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Lejla DarukaSynthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre Szeged, Szeged, H-6726, Hungary.
Tasvilla SonallyaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Tünde JuhászInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Rita HirmondóInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Imola Cs SzigyártóInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Loránd RománszkiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Natália TőkésiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Daniel PinkasCryo-Electron Microscopy and Tomography Core Facility, CEITEC, Masarykova University, Brno, Czech Republic.
Eszter HázyHUN-REN-ELTE Motor Pharmacology Research Group, Department of Biochemistry, Eötvös Loránd University, Budapest, Hungary.
Olivér PavelaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Andrea BodorELTE Eötvös Loránd University, Institute of Chemistry, Analytical and BioNMR Laboratory, Budapest, Hungary.
Zoltán VargaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
István MándityInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Mihály KovácsHUN-REN-ELTE Motor Pharmacology Research Group, Department of Biochemistry, Eötvös Loránd University, Budapest, Hungary.
Csaba PálSynthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre Szeged, Szeged, H-6726, Hungary.
Kata HorvátiMTA-HUN-REN TTK Lendület "Momentum" Peptide-Based Vaccines Research Group, Institute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Judit TóthInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Tamás Beke-SomfaiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.ORCID https://orcid.org/0000-0002-4788-3758

Funding

Development and Innovation OfficeELTE KMOP 4.2.1/B-10-2011-0002ELTE KMOP NKFIH K-134595European Research Council ERC-2023-ADG 101142626-FutureAntibioticsEuropean Union HORIZON WIDERA 2023 IDP2Biomed 101160233Hungary 144180Hungary 2020-1.1.2-PIACI-KFI-2020-00021Hungary K138318Hungary KKP_22Hungary TKP2021-EGA-31Lendület (Momentum) Programme of the Hungarian Academy of Sciences LP2021-28National Laboratory of Biotechnology 2022-2.1.1-NL-2022-00008National ResearchNational Research, Development and Innovation Office K146323
6 · The paper itself

Abstract

Artificial bioinspired supramolecular assemblies hold great potential to alter modern medicine. Organic tissue-like nanomaterials built from foldamer peptidomimetics and natural biomolecules could expand our boundaries toward new biocompounds that are able to address global health challenges. Related, antimicrobial resistance against conventional antibiotics motivates search for new compounds with orthogonal mechanisms. Here we designed an antibacterial system where natural adenosine phosphates (APs) trigger supramolecular co-assemblies from a lipopolysaccharide-targeting (LPS) antimicrobial β

Indexed as

Adenosine TriphosphateAnti-Bacterial AgentsAntimicrobial PeptidesDrug Resistance, Multiple, BacterialEscherichia coliNanofibersAdenosine TriphosphateAnti-Bacterial AgentsAntimicrobial Peptidesantibacterial mechanismantimicrobialsmulti‐drug resistancesupramoleculeβ‐peptide

Identifiers

PMID41852281
PMCPMC13185843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.