Evidence map›Paper›PMID 41852231›Full record

ReviewThe Journal of international medical research2026

Terbinafine-induced liver injury with isolated serum alkaline phosphatase elevation: A case report and literature review.

Yi-Hui Liu, Yan Guo, Hong Xu, Hui Feng, Feng Pan

Abstract readCase ReportsReview
In one paragraph

Review in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi-Hui LiuDepartment of Gastroenterology, Hangzhou Red Cross Hospital, China.ORCID 0000-0003-0399-0807
Yan GuoDepartment of Gastroenterology, Hangzhou Third Hospital, China.
Hong XuDepartment of Gastroenterology, Hangzhou Red Cross Hospital, China.
Hui FengDepartment of Gastroenterology, Hangzhou Red Cross Hospital, China.
Feng PanDepartment of Gastroenterology, Hangzhou Red Cross Hospital, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cholestatic drug-induced liver injury, serum liver function tests typically demonstrate concurrent elevations in alkaline phosphatase and γ-glutamyltransferase, with or without increases in alanine aminotransferase, aspartate aminotransferase, and total bilirubin. Isolated elevation of alkaline phosphatase is rare. Herein, we report a case of drug-induced liver injury characterized by isolated alkaline phosphatase elevation for clinicians. Following treatment with ursodeoxycholic acid, the patient achieved complete recovery. Clinicians should recognize that drug-induced liver injury may also present as an isolated elevation of alkaline phosphatase.

Indexed as

Alkaline PhosphataseAntifungal AgentsChemical and Drug Induced Liver InjuryNaphthalenesHumansLiverLiver Function TestsMaleMiddle AgedTerbinafineUrsodeoxycholic AcidAlkaline PhosphataseAntifungal AgentsNaphthalenesTerbinafineUrsodeoxycholic Acidalkaline phosphatasecases reportDrug-induced liver injuryreviewterbinafine

Identifiers

PMID41852231
PMCPMC13009991

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.