ArticleJournal of surgical oncology2026
Preoperative and Intraoperative Assessment of Extrathyroidal Extension in Unilateral Papillary Thyroid Carcinoma: Does It Necessitate Total Thyroidectomy?
Article in Journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundThe optimal surgical extent for papillary thyroid carcinoma (PTC) with extrathyroidal extension (ETE) suspected on ultrasound or intraoperative exploration remains debated. This study evaluated the diagnostic accuracy of clinical ETE (cETE) assessment and compared oncologic outcomes after lobectomy between cETE-positive and cETE-negative patients.
methodsThis single-center retrospective study enrolled 213 patients with PTC who underwent lobectomy. cETE was defined as tumor extension beyond the thyroid capsule on preoperative ultrasound or intraoperative exploration. Pathologically confirmed ETE served as the gold standard for determining the sensitivity, specificity, and accuracy of both ultrasound and intraoperative ETE assessments. Recurrence-free survival was compared between groups by different ETE features.
resultsPreoperative/intraoperative ETE assessments exhibited limited sensitivity (12.3% and 33.6%), limited accuracy (49.3% and 55.9%), and high specificity (98.9% and 85.7%). With a mean follow-up duration of 63.5 ± 11.7 months, the recurrence rates were recorded at 1.6% (1/61) in Group cETE+ in comparison to 2.0% (3/152) in Group cETE- (p = 0.871).
conclusionClinical ETE assessment has limited accuracy but high specificity. Lobectomy offers comparable oncologic outcomes regardless of cETE status, supporting its feasibility in selected PTC patients without mandating total thyroidectomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.