Evidence map›Paper›PMID 41852022›Full record

ArticleJournal of neurotrauma2026

Role of Polygenic Risk Scores in Predicting Cognitive Functioning after Mild Traumatic Brain Injury: A TRACK-TBI Study.

Lindsay D Nelson, Mary U Simons, Sonia Jain, Xiaoying Sun, Karmel Choi, Nancy Temkin, Ramon Diaz-Arrastia, Raquel Gardner, Sabrina Taylor, Geoffrey T Manley and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lindsay D NelsonDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Mary U SimonsDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Sonia JainHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USA.
Xiaoying SunHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USA.
Karmel ChoiDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Nancy TemkinDepartments of Neurological Surgery and Biostatistics, University of Washington, Seattle, Washington, USA.
Ramon Diaz-ArrastiaDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Raquel GardnerJoseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.
Sabrina TaylorDepartment of Neurological Surgery, University of California, San Francisco, California, USA.
Geoffrey T ManleyDepartment of Neurological Surgery, University of California, San Francisco, California, USA.
Murray B SteinHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USA.

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
Improving Patient Classification and Outcome Measurement in Traumatic Brain Injury (TBI)R01NS110856 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI NELSON, LINDSAY · 2019 to 2023
$3.0M
Integrating Health Records, Genomic, and Social Data to Stratify Adolescent Depression RiskK08MH127413 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, KARMEL · 2021 to 2025
$987k
NIMH NIH HHS K08 MH127413NINDS NIH HHS R01 NS110856NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

Patients with traumatic brain injury (TBI) and Glasgow Coma Scale scores of 13-15 (historically called mild TBI [mTBI]) commonly experience changes in cognitive functioning, including processing speed, memory, and executive functioning. In a prospective sample (

Indexed as

Brain ConcussionCognitionAdultFemaleGenetic Risk ScoreGlasgow Coma ScaleHumansIntelligenceMaleMiddle AgedNeuropsychological TestsProcessing SpeedPrognosisProspective Studiescognitive reserveeducationgeneticsneuropsychological outcomepolygenic risk scoreprotective factorstraumatic brain injury

Identifiers

PMID41852022
PMCPMC13108594

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.