Evidence map›Paper›PMID 41851764›Full record

ArticleMalaria journal2026

Cerebral malaria caused by Plasmodium vivax in an afrodescendant adult in Colombia: case report.

Andrés David Sastre-Martínez, Michael Andres García Gutiérrez, Raúl Andrés Vallejo-Serna, Jenny Patricia Muñoz-Lombo

Abstract readCase Reports
In one paragraph

Article in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrés David Sastre-MartínezInternal Medicine Department, Universidad del Valle, Cali, Colombia. andres.sastre@correounivalle.edu.co.
Michael Andres García GutiérrezIntensive Care Unit, Hospital Universitario del Valle "Evaristo García", Cali, Colombia.
Raúl Andrés Vallejo-SernaInfectious Diseases Department, Universidad del Valle, Cali, Colombia.
Jenny Patricia Muñoz-LomboInternal Medicine Department, Universidad del Valle, Cali, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria, caused by parasites of the Plasmodium genus and transmitted by Anopheles mosquitoes, remains a global public health issue, with a high incidence in tropical and subtropical regions. Although Plasmodium falciparum is the main cause of severe cases, Plasmodium vivax can also lead to serious complications, including cerebral malaria. CASE PRESENTATION: This case report presents the case of a 43-year-old woman from the southwestern Pacific coast, Colombia, who developed severe neurological symptoms with an initially unclear diagnosis. A thick blood smear confirmed P. vivax infection. She was treated with intravenous artesunate and subsequently with chloroquine and primaquine, and she achieved a full recovery.

conclusionsCerebral malaria has traditionally been associated with P. falciparum, P. vivax can also cause it through mechanical and inflammatory mechanisms, with a complex pathophysiology and potentially fatal outcomes. Early treatment with parenteral artesunate and intensive supportive care is key to improving outcomes.

Indexed as

Malaria, CerebralMalaria, VivaxPlasmodium vivaxAdultAntimalarialsArtesunateChloroquineColombiaFemaleHumansPrimaquineAntimalarialsArtesunateChloroquinePrimaquineCerebral malariaColombiaPlasmodium vivax

Identifiers

PMID41851764
PMCPMC13122863

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.