Evidence map›Paper›PMID 41851600›Full record

ArticleProteins2026

The X-Ray Crystal Structure of BorF, the Flavin Reductase Subunit of a Two-Component Flavin-Dependent Tryptophan Halogenase.

Zheng Ma, Emily W Rady, Aravinda J de Silva, John J Bellizzi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Zheng MaDepartment of Chemistry and Biochemistry, College of Natural Sciences and Mathematics, The University of Toledo, Toledo, Ohio, USA.
Emily W RadyDepartment of Chemistry and Biochemistry, College of Natural Sciences and Mathematics, The University of Toledo, Toledo, Ohio, USA.
Aravinda J de SilvaDepartment of Chemistry and Biochemistry, College of Natural Sciences and Mathematics, The University of Toledo, Toledo, Ohio, USA.
John J BellizziDepartment of Chemistry and Biochemistry, College of Natural Sciences and Mathematics, The University of Toledo, Toledo, Ohio, USA.ORCID https://orcid.org/0000-0003-4833-2795

Funding

Discovery and Characterization of Novel Halogenases from the Human Microbiome and from ArchaeaR15GM144877 · NIGMS · UNIVERSITY OF TOLEDO · PI BELLIZZI, JOHN J. · 2021 to 2025
$935k
Michigan Economic Development CorporationMichigan Technology Tri-Corridor 085P1000817NIGMS NIH HHS R15 GM144877NIH HHS R15GM144877
6 · The paper itself

Abstract

BorF is a short-chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH

Indexed as

Bacterial ProteinsFlavin-Adenine DinucleotideFMN ReductaseOxidoreductasesAmino Acid SequenceBinding SitesCrystallography, X-RayEscherichia coliModels, MolecularProtein BindingProtein Conformation, alpha-HelicalProtein MultimerizationProtein SubunitsRecombinant ProteinsBacterial ProteinsFlavin-Adenine DinucleotideFMN ReductaseOxidoreductasesProtein SubunitsRecombinant Proteinstryptophan halogenasebiosynthesiscrystallographyflavin adenine dinucleotideoxidoreductase

Identifiers

PMID41851600
PMCPMC13327496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.