Evidence map›Paper›PMID 41851550›Full record

ArticleObesity surgery2026

Achalasia and Esophageal Motility Disorders in the Bariatric Surgery Population: A Retrospective Descriptive Series.

Pattharasai Kachornvitaya, Melissa V Wills, Baraa K Mohamed, Valentin Mocanu, Juan S Barajas-Gamboa, Xinlei Zhu, Yung Lee, Ricard Corcelles, Andrew T Strong, Suthep Udomsawaengsup and 3 more

Abstract read
In one paragraph

Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pattharasai KachornvitayaDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Melissa V WillsDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Baraa K MohamedDepartment of Surgery, Northeast Georgia Medical Center, Gainesville, United States.
Valentin MocanuDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Juan S Barajas-GamboaDigestive Diseases Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Xinlei ZhuDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Yung LeeDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Ricard CorcellesDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Andrew T StrongDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Suthep UdomsawaengsupDepartment of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Salvador NavarreteDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Jerry DangDigestive Disease Institute, Cleveland Clinic, Cleveland, United States.
Matthew KrohDigestive Disease Institute, Cleveland Clinic, Cleveland, United States. krohm@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchalasia and severe obesity represent a rare but clinically challenging intersection. In patients undergoing bariatric surgery, esophageal motility disorders (EMDs), including achalasia and related conditions, may be pre-existing, unmasked, or develop following surgical alteration of foregut anatomy. Optimal treatment sequencing in this population remains poorly defined.

objectivesTo descriptively characterize clinical presentation, diagnostic features, and outcomes in patients treated for both severe obesity and EMDs, and to propose a preliminary treatment algorithm based on treatment sequencing.

methodsWe conducted a retrospective descriptive case series of patients treated between 2008 and 2023 at a single academic center. Among 7,054 patients who underwent primary sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB), 17 patients also underwent procedures for achalasia and EMDs were included. Patients were categorized by treatment sequence: achalasia treatment first (AF), bariatric surgery first (BF), or concurrent treatment.

resultsThe cohort had a mean age of 56.9 years and was predominantly female (70.6%). Type II achalasia was most common (41.2%). Patients treated for achalasia before or concurrently with bariatric surgery (n = 9) demonstrated generally favorable outcomes, with 12-month percentage total weight loss (%TWL) ranging from 20.2% to 49.6% and sustained symptom control in 66.7%. In contrast, patients treated for achalasia or EMDs after bariatric surgery (n = 8) experienced more heterogeneous clinical courses, with frequent need for additional interventions and variable symptom control, particularly following SG. Esophageal dysfunction occurred earlier after SG than after RYGB, and three of four SG patients (75%) required conversion to RYGB.

conclusionsIn this small descriptive series, treatment sequencing appeared to influence clinical outcomes in patients with severe obesity and achalasia or EMDs. Given the diagnostic complexity and heterogeneity of this population, these findings should be interpreted as hypothesis-generating. Larger, multicenter studies with standardized diagnostic criteria are needed to inform evidence-based management strategies.

Indexed as

Bariatric SurgeryEsophageal AchalasiaEsophageal Motility DisordersObesity, MorbidAdultFemaleGastric BypassHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAchalasiaBariatric surgeryEsophageal motility disordersHeller myotomyObesityPOEMSurgical algorithm

Identifiers

PMID41851550
PMCPMC13083340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.