ArticleNature2026
Proteasome-guided haem signalling axis contributes to T cell exhaustion.
Erratum issuedAbstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Article
- Tumor-driven stabilization of CD8Frontiers in immunology · 2026Review
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
31 authors.
Yingxi XuDepartment of Oncology, University of Lausanne, Lausanne, Switzerland. xuyingxi@ihcams.ac.cn.ORCID http://orcid.org/0000-0002-0056-7440
Yangtao ShangguanState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Yu-Ming ChuangDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Tzu-Hsuan ChangDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-0455-3107
Wenbing LiuState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.ORCID http://orcid.org/0000-0003-4562-5541
Jhan-Jie PengDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Josep GarnicaDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-9493-1321
Leling XieState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Pei-Chun HsuehDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Mei-Chun LinDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Yi-Hao WangDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0009-0004-3972-4206
Karina Lobo HajduDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-9655-3870
Yibo WuChemical Biology Mass Spectrometry Platform (CHEMBIOMS), Faculty of Sciences, University of Geneva, Geneva, Switzerland.
Maryam AkramiLaboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0001-6450-8442
Chen WangDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID http://orcid.org/0000-0003-2271-5587
Anna KohlDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Alfred ZippeliusLaboratory of Cancer Immunology, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0003-1933-8178
Wei QiNovogene Co. Ltd, Beijing, China.
Min WangState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Bugi Ratno BudiartoInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Shih-Yu ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-7955-481X
Zhengtao XiaoSchool of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Panagiota VardakaDepartment of Pathology, University of Cambridge, Cambridge, UK.
Rahul RoychoudhuriDepartment of Pathology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-5392-1853
Zhiliang BaiDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-3977-3057
Rong FanDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-7805-8059
Santiago CarmonaDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-2495-0671
Yi-Ru YuDepartment of Oncology, University of Lausanne, Lausanne, Switzerland.
Christoph ScheiermannDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-9212-0995
Jianxiang WangState Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. wangjx@ihcams.ac.cn.ORCID http://orcid.org/0000-0001-9437-9151
Ping-Chih HoDepartment of Oncology, University of Lausanne, Lausanne, Switzerland. ping-chih.ho@unil.ch.ORCID http://orcid.org/0000-0003-3078-3774
Funding
No grant is acknowledged in the PubMed record.
Abstract
The accumulation of depolarized mitochondria commits T cells to exhaustion
Indexed as
CD8-Positive T-LymphocytesHemeProteasome Endopeptidase ComplexSignal TransductionAnimalsBortezomibFemaleHumansImmunotherapy, AdoptiveMaleMiceMitochondriaMitochondrial ProteinsPrecursor Cell Lymphoblastic Leukemia-LymphomaProteasome InhibitorsProteolysisBortezomibHemeMitochondrial ProteinsProteasome Endopeptidase ComplexProteasome InhibitorsReceptors, Chimeric Antigen
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.