Evidence map›Paper›PMID 41851453›Full record

ArticleNature2026

Synthetic circuits for cell ratio control.

Bolin An, Tzu-Chieh Tang, Qian Zhang, Teng Wang, Yanyi Wang, Kesheng Gan, Kun Liu, Daniel L Zhang, Yuzhu Liu, Yu Kui Pan and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Bolin An *State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0009-0003-2750-2609
Tzu-Chieh Tang *Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. zijaytang@gmail.com.ORCID http://orcid.org/0000-0002-6215-8714
Qian Zhang *State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Teng WangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID http://orcid.org/0009-0000-5176-5095
Yanyi WangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Kesheng GanState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Kun LiuState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Daniel L ZhangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yuzhu LiuState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yu Kui PanState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Min YuState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
William M ShawBiological Design Center, Boston University, Boston, MA, USA.
Qianyi LiangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yaomin WangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Christopher A VaianaSynthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Chunbo LouState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Christopher A VoigtSynthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-0844-4776
Timothy K LuSynthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
George M ChurchWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. gchurch@genetics.med.harvard.edu.ORCID http://orcid.org/0000-0001-6232-9969
Chao ZhongState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. chao.zhong@siat.ac.cn.ORCID http://orcid.org/0000-0002-6638-3652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in genetic engineering have provided diverse tools for artificially diversifying both prokaryotic and eukaryotic cell populations

Indexed as

Genetic EngineeringSaccharomyces cerevisiaeSynthetic BiologyAnimalsCell AdhesionCell DifferentiationCelluloseFermentationHumansPigmentationRecombinasesRecombination, GeneticCelluloseRecombinases

Identifiers

PMID41851453
PMCPMC13171440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.