Evidence map›Paper›PMID 41850748›Full record

ArticleAPMIS : acta pathologica, microbiologica, et immunologica Scandinavica2026

Tagitinin C-Rich Extract From Tithonia diversifolia (hemsl.) A. Gray Exerts Activity Against Pathogenic Bacteria and Biofilms.

Marianne Celestino Andrade, Rayane Andrade Santana Freitas, Helton Caio Santana Santos, Matheus Antoni da Silva Costa, Ricardo Luiz Cavalcanti de Albuquerque-Junior, Lívia Maria do Amorim Costa Gaspar, Agenor Gomes Dos Santos-Neto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marianne Celestino AndradePostgraduate Program in Biosciences and Health, Tiradentes University, Aracaju, Sergipe, Brazil.ORCID https://orcid.org/0009-0005-4069-040X
Rayane Andrade Santana FreitasInstitute of Technology and Research, Tiradentes University, Aracaju, Sergipe, Brazil.ORCID https://orcid.org/0009-0001-3051-4278
Helton Caio Santana SantosInstitute of Technology and Research, Tiradentes University, Aracaju, Sergipe, Brazil.ORCID https://orcid.org/0009-0009-7554-5199
Matheus Antoni da Silva CostaPostgraduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.ORCID https://orcid.org/0009-0000-3362-2170
Ricardo Luiz Cavalcanti de Albuquerque-JuniorDepartment of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0003-4444-7632
Lívia Maria do Amorim Costa GasparDepartment of Medicine, Tiradentes University, Aracaju, Sergipe, Brazil.ORCID https://orcid.org/0000-0002-4177-5086
Agenor Gomes Dos Santos-NetoPostgraduate Program in Biosciences and Health, Tiradentes University, Aracaju, Sergipe, Brazil.ORCID https://orcid.org/0000-0003-3698-1456

Funding

Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES)Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina
6 · The paper itself

Abstract

The increasing prevalence of persistent and difficult-to-treat infections has intensified interest in natural compounds able to act on both planktonic bacteria and biofilm structures. Tithonia diversifolia, a species rich in bioactive metabolites such as tagitinin C, has emerged as a promising source of antimicrobial agents. This study evaluated the antibacterial and antibiofilm activities of a tagitinin C-rich leaf extract and potential mechanisms of action. The extract was obtained by supercritical CO

Indexed as

Anti-Bacterial AgentsAsteraceaeBiofilmsPlant ExtractsEnterococcus faecalisMicrobial Sensitivity TestsMolecular Docking SimulationPlant LeavesPseudomonas aeruginosaSesquiterpenesStaphylococcus aureusAnti-Bacterial AgentsPlant ExtractsSesquiterpenestagitininantibacterial agentsAsteraceaepharmacodynamicsplant extractssesquiterpene

Identifiers

PMID41850748
PMCPMC12999292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.