In one paragraphArticle in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Rianne G BoumaDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Willem-Jan de LeeuwDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0000-0001-8172-6804 Aru Z WangDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Muddassir MalikDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Joeke Gc StolwijkDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Veronique Al KonijnDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-1965-1044 Natalie ProostDivision of Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0009-0001-3282-793X Maarten K Nijen TwilhaarDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Tibor van WelsemDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.ORCID 0009-0002-5875-1600 Negisa Seyed ToutounchiDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Alsya J AffandiDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-0859-2322 Fred van LeeuwenDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands fred.v.leeuwen@nki.nl.ORCID 0000-0002-7267-7251 Joke Mm den HaanDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands j.denhaan@amsterdamumc.nl.ORCID 0000-0002-4421-6917 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Dendritic cells (DCs) orchestrate immune responses. Their development is controlled by transcription factors, but epigenetic mechanisms remain poorly understood. DOT1L emerges as a key epigenetic regulator in immune cells. Mapping DOT1L-mediated histone H3K79 methylation in canonical DC subsets revealed that DOT1L modified common and DC subset-specific genes. Deletion of
Indexed as
Dendritic CellsHistone-Lysine N-MethyltransferaseAnimalsAntigen PresentationCell DifferentiationEpigenesis, GeneticHistonesMethylationMiceMice, Inbred C57BLMice, KnockoutDot1l protein, mouseHistone-Lysine N-MethyltransferaseHistones
Identifiers
PMID41850725
PMCPMC13000122
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