ArticleCellular and molecular gastroenterology and hepatology2026
Interleukin 6 Drives Durable T Cell-Mediated Immunity to Pancreatic Cancer.
Article in Cellular and molecular gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Interleukin-6: The Unexpected Opponent to Pancreatic Cancer.Cellular and molecular gastroenterology and hepatology · 2026Article
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Authors and funding
16 authors.
Funding
Abstract
BACKGROUND &
aimsTumor immune resistance is recognized as a contributor to low survivorship in pancreatic ductal adenocarcinoma (PDAC). The inflammatory cytokine interleukin-6 (IL-6) promotes polarization of CD4 T cell populations away from immune tolerance, and induces differentiation of cytotoxic CD8 T cells. This work aims to test whether IL-6 could stimulate an anti-tumor response in PDAC
methodsWe overexpressed IL-6 in multiple Kras
resultsImproved survival occurred in all instances of OT-PDAC
conclusionsLocally high IL-6 concentrations potently enhance the T cell-mediated anti-tumor response to PDAC.
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Registered trials
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