Evidence map›Paper›PMID 41850624›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2026

Factors associated with antibiotic prescription among patients with respiratory illness in Thailand: The potential impact of rapid influenza diagnostic testing in antimicrobial stewardship.

Chanakan Duanyai, Wanitchaya Kittikraisak, Visal Moolasart, Phunlerd Piyaraj, Pornsak Yoocharoen, Nattaprang Nittayasoot, Kathrine R Tan, William W Davis, Suthat Chottanapund

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Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Chanakan DuanyaiField Epidemiology Training Program, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Wanitchaya KittikraisakInfluenza Program, Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand. Electronic address: glr9@cdc.gov.
Visal MoolasartBamrasnaradura Infectious Diseases Institute, Nonthaburi, Thailand.
Phunlerd PiyarajDepartment of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Pornsak YoocharoenDepartment of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Nattaprang NittayasootField Epidemiology Training Program, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Kathrine R TanInfluenza Division, U.S. Centers for Disease Control and Prevention, Georgia, USA.
William W DavisInfluenza Program, Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand; Influenza Division, U.S. Centers for Disease Control and Prevention, Georgia, USA.
Suthat ChottanapundDepartment of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesOveruse of antibiotics is one of the drivers of antimicrobial resistance, especially in acute respiratory tract infection. We examined factors associated with antibiotic prescription among patients treated at two Thai hospitals during 2018-2022.

methodsMedical records of patients with respiratory illness were reviewed to abstract demographics, clinical features, diagnostics, treatments, and outcomes. Factors associated with antibiotic prescribing were assessed. Inappropriate use was defined as antibiotic receipt without laboratory-confirmed bacterial infection, severe symptoms, or clinically suspected bacterial pneumonia.

resultsAmong 905 inpatients and 1811 outpatients, 46.7% and 31.9% received antibiotics, of which 7.8% and 45.1% were inappropriate, respectively. In-hospital antibiotic use was stable in 2018-2020 (59.0-64.0%) before declining sharply in 2022 (22.7%). Outpatient antibiotic use was stable in 2018-2019 (36.3-29.0%), increased in 2020-2021 (41.8-41.7%), and declined in 2022 (11.5%). Patients aged >65 years (adjusted relative risk [aRR] 1.30); males (aRR 1.11); and those with unstable vital signs (aRR 1.18), ancillary testing (aRR 1.37), hospitalization (aRR 1.23), or bacterial infection (aRR 1.71) had higher odds of receiving antibiotics. Children aged 1 year (aRR 0.81), those with a positive rapid influenza diagnostic test (aRR 0.32), and those treated at a study hospital (aRR 0.83) were less likely to receive antibiotics. Antiviral treatment was associated with lower antibiotic use in 2021-2022 (aRR 0.44 and 0.19) but not in 2019-2020.

conclusionAntibiotic use among patients with respiratory illness was common, although nearly half of outpatient prescriptions were inappropriate. A positive result from rapid influenza diagnostic test was associated with reduced antibiotic prescribing.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipInappropriate PrescribingInfluenza, HumanRespiratory Tract InfectionsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDrug PrescriptionsFemaleHumansInfantMaleAnti-Bacterial AgentsAntibioticsInfluenzaRapid testThailand

Identifiers

PMID41850624
PMCPMC13105422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.