Evidence map›Paper›PMID 41850174›Full record

ArticleInternational dental journal2026

Automated Tooth Detection and Caries Identification in CBCT With Deep Learning.

Surong Chen, Weiwei Wu, Pan Chen, Gengyu Zhou, Yan Yang, Bowen Shen, Jingyu Hu, Jingzhi Ma

Abstract read
In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Surong ChenDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Weiwei WuDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pan ChenDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gengyu ZhouDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yan YangDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bowen ShenSchool of Artificial Intelligence and Automation, Huazhong University of Science and Technology, Wuhan, China.
Jingyu HuDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: 2014tj0116@hust.edu.cn.
Jingzhi MaDepartment of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: majingzhi@hust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDeep learning networks have achieved significant progress in caries diagnosis, but automated localization and numbering of carious teeth in cone-beam computed tomography (CBCT) images remain underexplored. This study aimed to develop a two-stage deep learning framework for tooth detection, numbering, and caries identification in CBCT images, providing a technical basis for automated analysis in support of opportunistic caries screening.

methodsThis retrospective study included CBCT images from 65 eligible patients. Axial slices were used for model development. For tooth detection, seven classification schemes were designed, and YOLOv3 was compared with Cascade R-CNN. For caries identification, three classification networks (DenseNet169, MobileNet_V2, and ResNet50) were trained and evaluated. Detection performance was evaluated using mean average precision (mAP) and average precision (AP). Identification performance was assessed using balanced accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), Matthews correlation coefficient (MCC), and area under the precision-recall curve (AUC-PR).

resultsYOLOv3 achieved superior detection performance compared with Cascade R-CNN across all classification schemes (P < .0001). DenseNet169 outperformed the other networks for caries identification. Despite class imbalance, it achieved a balanced accuracy of 0.7414 and an MCC of 0.6074, with high specificity (0.9828) and NPV (0.8976). The integrated two-stage framework showed acceptable overall performance.

conclusionThe proposed two-stage framework showed promising performance in detecting, numbering, and identifying caries in CBCT images, supporting the feasibility of adjunctive opportunistic screening on scans acquired for non-caries indications. CLINICAL RELEVANCE: This framework may help prioritize clinician review of CBCT scans for suspected carious lesions, and clinical utility requires external multi-center and prospective validation.

Indexed as

Cone-Beam Computed TomographyDeep LearningDental CariesConvolutional Neural NetworksDetection AlgorithmsHumansRetrospective StudiesSensitivity and SpecificityCaries identificationCone-beam computed tomographyDeep learningTooth detection

Identifiers

PMID41850174
PMCPMC13011194

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.