Evidence map›Paper›PMID 41849750›Full record

ArticleHepatology (Baltimore, Md.)2026

Clinical guideline for the diagnosis and treatment of fibrolamellar carcinoma.

Allison F O'Neill, Emily L Zeme, Ghassan K Abou-Alfa, Marina Baretti, Alexander J Bondoc, Alanna Church, Cristina R Ferrone, Megan Fitzgerald, James I Geller, Anne E Gill and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hepatology (Baltimore, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Allison F O'NeillDana-Farber and Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, USA.
Emily L ZemeUniversity of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.
Ghassan K Abou-AlfaMemorial Sloan Kettering Cancer Center, New York, New York, USA.
Marina BarettiDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Alexander J BondocCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Alanna ChurchDepartment of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA.
Cristina R FerroneDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-6295-1085
Megan FitzgeraldDepartment of Pediatric Psychosocial Care, Dana-Farber and Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts, USA.
James I GellerPeckham Center for Cancer and Blood Disorders, Rady Children's Hospital, San Diego, California, USA.
Anne E GillDepartment of Radiology and Imaging Sciences, Division of Interventional Radiology and Image-Guided Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
William P HarrisUniversity of Washington, School of Medicine, Seattle, Washington, USA.
Heung Bae KimDepartment of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Sunyoung S LeeDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kevin X LiuDepartment of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2071-5137
Michael V OrtizDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Arun RangaswamiDepartment of Pediatrics, Division of Pediatric Hematology and Oncology, University of California San Francisco, San Francisco, California, USA.
Kimberly J RiehleDepartment of Surgery, University of Washington and Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, Seattle, Washington, USA.
Abby R RosenbergDepartment of Supportive Oncology, Dana-Farber Institute, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-7608-607
Michael S TorbensonDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Mark YarchoanJohns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
John D GordanUniversity of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA.ORCID 0000-0001-8997-5725

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Project 4: ImmunovirotherapyP50CA210964 · NCI · MAYO CLINIC ROCHESTER · PI Zongming Eric Chen · 2018 to 2026
$20.5M
Pediatric Preclinical In Vivo Testing Center for Pediatric Sarcoma and Other Solid TumorsU01CA263967 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Filemon S Dela Cruz, ANDREW L KUNG · 2021 to 2026
$4.0M
Targeting Oncogenic PKA signaling mechanismsR01CA279997 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI John D Gordan, John D Scott · 2024 to 2026
$1.9M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA210964NCI NIH HHS R01 CA279997NCI NIH HHS U01 CA263967
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adolescent/young adultdebulking surgeryfibrolamellar carcinomafibrolamellar hepatocellular carcinomaliver cancermolecular geneticssystemic therapy

Identifiers

PMID41849750
PMCPMC13307593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.