Evidence map›Paper›PMID 41849664›Full record

ArticleJMIR medical informatics2026

Dynamic Personalized Optimization: An AI Functionality Framework for Digital Therapeutics.

Dohyoung Rim

Abstract read
In one paragraph

Article in JMIR medical informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Dohyoung RimRowan Corporation, 18F Yonsei Severance Bld, 10, Tongil-ro, Jung-gu, Seoul, 04527, Republic of Korea, 82 2-6731-0810, 82 2-6930-5606.ORCID 0000-0003-2022-6333

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unlabelled: Dynamic Personalized Optimization (DPO) is introduced as a conceptual framework that defines core artificial intelligence (AI) functions required to deliver real-time, personalized, and optimized treatment in digital therapeutics (DTx). DPO continuously refines therapeutic strategies by integrating patient data, treatment content, usage feedback, and status measurements to provide real-time, personalized treatment. Using predictive AI models, DPO adapts treatment approaches based on patient responses, thereby improving therapeutic effectiveness. Furthermore, this paper explores the potential role of large language models (LLMs) in supporting DPO by processing diverse and complex data formats. By addressing current limitations in real-time personalization within DTx, DPO establishes a structured, AI-driven approach to delivering tailored digital interventions. This framework ultimately aims to enhance treatment efficacy and improve patient engagement.

Indexed as

Artificial IntelligencePrecision MedicineTherapeuticsDigital HealthHumansLarge Language ModelsAI functionality frameworkdigital therapeuticsdynamic personalized optimizationlarge language modelspersonalized treatment

Identifiers

PMID41849664
PMCPMC12998713

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.