Evidence map›Paper›PMID 41849632›Full record

SynthesisObesity facts2026

Effects of Bariatric Surgery in Individuals with PTEN Hamartoma Tumor Syndrome: A Systematic Review.

Isela N Oceguera, Wah Yang, Chetan Parmar, Suhaib J S Ahmad, Sjaak Pouwels

Abstract readSystematic Review
In one paragraph

Synthesis in Obesity facts, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isela N OcegueraUniversity of Guadalajara, Health Sciences University Center, Guadalajara, Mexico.
Wah YangDepartment of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Chetan ParmarDepartment of Surgery, Whittington Hospital, London, UK, c.parmar@ucl.ac.uk.
Suhaib J S AhmadDepartment of General Surgery, Betsi Cadwaladr University Health Board, Wrexham, UK.
Sjaak PouwelsDepartment of Surgery, University Hospital OWL of Bielefeld University - Campus Klinikum Lippe, Detmold, Germany, sjaakpwls@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this systematic review was to provide an overview of the literature on the effects of bariatric surgery in patients with obesity and phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) diagnosis.

methodsA systematic literature search was conducted using the search word PHTS and Bariatric Surgery, modified for each database. Studies were included if they investigated the effects of bariatric surgery in patients with bariatric surgery.

resultsTwo studies were included with a methodological quality ranging from poor to good. Both studies were case reports in young females (<35 years old), and massive effects on weight loss and HbA1c levels were seen. Bariatric surgery in obese patients with PHTS diagnosis results in significant decrease in weight and complete remission of diabetes mellitus type 2. The effects on thyroid hormones, lipid levels, renal function, and psychological factors after bariatric surgery in PHTS remain unexplored.

conclusionMore research is needed to fully understand how bariatric surgery can take part of the preventative treatment options for PHTS patients with obesity.

Indexed as

Bariatric surgeryDiabetes mellitus type 2Hamartoma tumor syndromeObesityPhosphatase and tensin homologPTEN geneWeight loss surgery

Identifiers

PMID41849632
PMCPMC13075960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.