Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Ju-Sim KimDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0002-4932-4490
Vijay KumarDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Lin LiuDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.
Yu J ChoiUniversity of Colorado Cancer Center, University of Colorado, Aurora, CO, USA.
Simona SenovaityteDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.ORCID 0009-0009-2086-9911
Bruce D McCollisterDepartment of Medicine, Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO, USA.
Nathan WlodarchakDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0001-8549-4369
David J OrlickyDepartment of Pathology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0002-0417-1400
Peter J RiceDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.ORCID 0000-0002-0707-0138
Shaodong DaiDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0003-4760-2773
Michael F WempeDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.ORCID 0000-0002-8157-5281
Andrés Vázquez-TorresDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0002-6181-4185
Funding
Molecular determinants of oxidative stress in Salmonella pathogenesisR01AI136520 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Andres Vazquez-Torres · 2018 to 2026
$3.7M
Phage/Salmonella interactions during oxidative stressR01AI190189 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2025 to 2025
$2.7M
Characterization of disulfide modified diabetogenic neoepitopesR01DK137056 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI SHAODONG DAI · 2023 to 2026
$1.8M
BLRD VA I01 BX002073NIAID NIH HHS R01 AI136520NIAID NIH HHS R01 AI190189NIDDK NIH HHS R01 DK137056ORD VA IK6 RD001354
6 · The paper itself
Abstract
We are in dire need of antibiotics endowed with new mechanisms of action. The DksA protein regulates the transcription of genes involved in metabolism, translation, and virulence in Gram-negative bacteria. DksA is evolutionarily conserved among Gram-negative pathogens but is absent in humans. Here, we identified a conserved acidic pocket at the tip of the coiled-coil domain of DksA that is amenable for drug development. Our bioinformatics and experimental approaches identified
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
DksA inhibitors against intracellular and persistent · full record | OpenQuestion