ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2026
Trend and burden of lower-limb amputations due to diabetes: time series analysis, Amazonas, 2012-2021.
Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo calculate the temporal trend and the burden of disease for lower-limb amputations due to diabetes in Amazonas, Brazil, from 2012 to 2021.
methodsThis is a time series analysis study using data from the Hospital Information System of the Brazilian Unified Health System. Specific and age-adjusted rates, the annual percent change of amputations, and the 95% confidence interval were calculated for the period 2012-2021. Years lived with disability were calculated and stratified by sex and age group between 2017 and 2021.
resultsDuring the 10 years analyzed, 3,621 lower-limb amputation procedures were performed in people with diabetes in public hospitals in Amazonas. An increase in age-adjusted amputation rates among men was observed, rising from 8.33 per 100 thousand men in 2012 to 15.55 per 100 thousand men in 2021, with an annual percent change of 10.5% and a 95% confidence interval between 3.8% and 17.6%. The disease burden totaled 21,845.11 years lived with disability, of which 70.4% corresponded to men. Most years lived with disability were concentrated in the 45-64 age group (58.2%).
conclusionThere was a male predominance in the increasing trend of lower-limb amputations and in the high burden of disease in Amazonas.
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