Evidence map›Paper›PMID 41849029›Full record

ReviewFood science of animal resources2026

Novel food processing technologies to reduce egg allergenicity: a review from allergen digestion to IgE-mediated responses.

Chemin Nam, So Eun Yeo, Rina Yu, Prabhathma Yasasvi Rathnayake, Haeeun Park, Sehyeok Oh, Hae In Yong

Abstract readReview
In one paragraph

Review in Food science of animal resources, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chemin NamDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
So Eun YeoDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
Rina YuDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
Prabhathma Yasasvi RathnayakeDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
Haeeun ParkDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
Sehyeok OhDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of.
Hae In YongDepartment of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, Korea, Republic of. yonghaein@cnu.ac.kr.

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry (IPET) Project No. RS-2025-02310241National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) Project No. RS-2025-24523920
6 · The paper itself

Abstract

Eggs are a high-quality nutrient source that is widely used in food products. However, eggs are also recognized as allergenic foods that can induce severe allergic reactions, particularly in infants and children. Egg allergies are primarily caused by six egg allergens (ovomucoid, ovalbumin, ovotransferrin, lysozyme, alpha-livetin, and YGP42). During gastrointestinal digestion, the structures of egg allergens are altered by enzymatic hydrolysis and absorbed into the body. Certain absorbed allergens retain immunoglobulin E (IgE)-specific epitopes that can interact with IgE and elicit an IgE-mediated immune response. To date, various food processing technologies, including glycation, ultrasound, pulsed electric field, irradiation, high-pressure processing, and cold plasma, have been widely reported as new approaches for reducing egg allergenicity. These processing technologies can alleviate egg allergenicity by altering the linear and/or conformational epitopes, thereby decreasing IgE binding capacity. Therefore, this review examines the influence of processing technologies on egg allergenicity and how these technologies influence the allergenicity of egg allergens during gastrointestinal digestion.

Indexed as

Egg allergyFood processingGastrointestinal digestionIgE-mediated immune response

Identifiers

PMID41849029
PMCPMC12995051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.