ArticleFood science of animal resources2026
Improved antioxidant and anti-melanogenic effects of ovalbumin derived from egg white after enzymatic hydrolysis.
Article in Food science of animal resources, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Consumption of oxidized foods or exposure of skin to ultraviolet (UV) can produce reactive oxygen species (ROS) that increase oxidative stresses that can lead to skin aging and melanogenesis. Hydrolyzing proteins like ovalbumin (OA) can significantly increase their bioactivities. In this study, OA was hydrolyzed using Alcalase 2.4 L FG, Multifect PR 14 L, and Papain T100 MG, and the antioxidant and melanogenesis inhibitory activities of the hydrolysates were determined using B16F10 melanoma cells. All OA hydrolysates (OAH) showed higher antioxidant activities than the natural OA. The OAH prepared with Multifect PR 14 L (OAMF) exhibited the highest antioxidant activities and significantly inhibited melanin production and tyrosinase activity in the stimulated B16F10 cells using α-melanocyte-stimulating hormone. The DOPA staining confirmed the melanogenesis inhibitory (melanin formation and dendrite development) effects of OAMF. The OAMF (100, 200, and 400 µg/mL) treatment downregulated the mRNA expression of microphthalmia-associated transcription factor (MITF) and melanogenic enzymes [tyrosinase, tyrosinase-related protein 1 (TRP-1), and tyrosinase-related protein 2 (TRP-2)] dose-dependently. Therefore, OAMF can help reduce oxidative stress in humans when consumed and can be used as an anti-aging and skin-lightening agent in the cosmetic industry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.