Evidence map›Paper›PMID 41848818›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2026

Real-World Cohort Study of Semaglutide in Adults with Type 2 Diabetes Using an Electronic Health Records Database in Tianjin, China.

Shanshan Wang, Ping Hu, Zewei Shen, Liming Chen

Registry-linked trialAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT06351748. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06351748 completed

Real-world Study of CHina Ozempic cLinicAl pRactice in Patients With Type 2 Diabetes (SCHOLAR)

Ran2024Enrolled34,238Registered outcomes12Posted comparisons0ConditionsDiabetes Mellitus, Type 2Armssemaglutide
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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shanshan WangNHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, 6 Huanrui-Bei Road, Tianjin, 300134, China.
Ping HuNovo Nordisk (Shanghai), 5F, Tower 3, Lei Shing Hong Center, No. 8, Guangshunnan Avenue, Chaoyang District, Beijing, 100102, China.
Zewei ShenNovo Nordisk (Shanghai), 5F, Tower 3, Lei Shing Hong Center, No. 8, Guangshunnan Avenue, Chaoyang District, Beijing, 100102, China.
Liming ChenNHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, 6 Huanrui-Bei Road, Tianjin, 300134, China. xfx22081@vip.163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to evaluate changes in clinical parameters among adults with type 2 diabetes (T2D) after initiating subcutaneous semaglutide in Chinese clinical practice.

methodsSCHOLAR was a retrospective cohort study using data from the Tianjin regional electronic health records database, including adults with T2D who initiated once-weekly semaglutide (full analysis set [FAS]). Endpoints included change in glycated hemoglobin (HbA

resultsAmong 26,859 individuals (FAS), mean ± SD age was 57 ± 13 years, and duration of T2D was 4 ± 3 years. Individuals with HbA

conclusionsInitiating once-weekly semaglutide was associated with significant improvements versus baseline in glycemic control and lipids in people with T2D from Tianjin, China. Safety of semaglutide was similar to the established safety profile per adverse events assessment. CLINICAL TRIALS REGISTRATION: NCT06351748.

Indexed as

Chinese populationGLP-1RAReal-world dataSemaglutideType 2 diabetes

Identifiers

PMID41848818
PMCPMC13103031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.