Evidence map›Paper›PMID 41848817›Full record

ReviewFood science of animal resources2026

Utilization of animal by-products as sources of bioactive compounds and FBS alternatives for cultured meat: a comprehensive review.

Juhyun Lee, Da-Young Lee, Ermie Jr Mariano, Ji Won Park, Seok Namkung, So Young Choi, Woo Jin Lee, Ye Won Shin, Chae Hyeon Bok, Colin Venter and 2 more

Abstract readReview
In one paragraph

Review in Food science of animal resources, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juhyun LeeDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Da-Young LeeDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Ermie Jr MarianoDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Ji Won ParkDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Seok NamkungDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
So Young ChoiDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Woo Jin LeeDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Ye Won ShinDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Chae Hyeon BokDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Colin VenterDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Younsu LeeDepartment of Pet Health, Kwangju Women's University, 40 Gwangjuyeodai-gil, Gwangsan-gu, Gwangju, 62396, Republic of Korea.
Sun Jin HurDepartment of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea. hursj@cau.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Slaughterhouse by-products have been widely utilized in food, pharmaceutical, and biomaterial applications across Asia, Europe, and the Americas. This review examines current research on enhancing the value and utilization of these by-products, with a particular focus on their potential as alternatives to fetal bovine serum (FBS), a critical component of cell culture media. Among these, livestock and poultry blood-produced at over 30 million tons annually-is of particular interest; however, only approximately 30% is currently used in food products or additives. Recent studies suggest that serum derived from bovine, porcine, and chicken blood may serve as viable substitutes for FBS. Recent studies have suggested that serum derived from adult bovine, porcine, and chicken blood may partially substitute for FBS, with replacement efficiencies reported to reach up to approximately 80%, depending on the species. Inedible by-products, including feathers, bones, leather, and hooves, are primarily processed into fertilizers and animal feed due to their high protein and mineral content. Despite the considerable volume of slaughter by-products generated, their application in cell culture systems and other high-value industries remains underdeveloped. Promoting the industrial utilization of these materials could not only improve resource efficiency and reduce environmental impact but also contribute to the sustainability and economic value of the livestock sector.

Indexed as

Animal bloodCell culture mediaCultured meatFetal bovine serumSlaughterhouse by-productsWaste valorization

Identifiers

PMID41848817
PMCPMC12995063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.