Evidence map›Paper›PMID 41848413›Full record

ArticleDrug and alcohol review2026

Factors Associated With Opioid Agonist Treatment Engagement and Harm Reduction Service Use: Findings From the New South Wales Opioid Dependence Survey.

Thomas Santo, Chrianna Bharat, Craig Rodgers, Mary Harrod, Sophia Taylor, Emma Zahra, Rachel Sutherland, Amy Peacock, Jason Grebely, Matthew Hickman and 2 more

Abstract read
In one paragraph

Article in Drug and alcohol review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas SantoNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-1218-3946
Chrianna BharatNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-9778-0386
Craig RodgersAlcohol and Drug Services, St Vincent's Hospital, Sydney, Australia.
Mary HarrodThe NSW Users and AIDS Association, Sydney, Australia.ORCID 0000-0001-8763-3115
Sophia TaylorNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0009-0002-4676-3233
Emma ZahraNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0001-6646-1633
Rachel SutherlandNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0001-5337-1751
Amy PeacockNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-5705-2026
Jason GrebelyThe Kirby Institute, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-1833-2017
Matthew HickmanNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0001-9864-459X
Michael FarrellNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.
Louisa DegenhardtNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-8513-2218

Funding

TRANSFORM - Transforming the evidence base on estimating prevalence of opioid use disorder and expanded access to interventions to prevent drug related deaths: an international data linkage studyR01DA059822 · NIDA · UNIVERSITY OF NEW SOUTH WALES · PI Joshua Adam Barocas, Louisa Degenhardt · 2024 to 2026
$2.3M
Australian Government Department of HealthAustralian National Health and Medical Research Council (NHMRC) Program 1150078Department of Health and Aged Care, Australian GovernmentNational Drug and Alcohol Research Centre, UNSW SydneyNational Health & Medical Research Council 1135991National Health & Medical Research Council 1176131National Health & Medical Research Council 2016825National Health & Medical Research Council 2034002NIDA NIH HHS 1R01DA059822-01A1NIDA NIH HHS R01 DA059822
6 · The paper itself

Abstract

introductionOpioid agonist treatment (OAT) is one of the most effective treatments for opioid dependence, but there can be barriers to accessing treatment. This study examined characteristics associated with OAT engagement-never, previous or current-among people with opioid dependence in NSW, Australia, following recent reforms to OAT access.

methodsBetween October 2023 and March 2024, people with opioid dependence were recruited from services and community settings across NSW. Participants completed structured interviews on socio-demographics, mental health disorders, substance use and use of prevention and treatment services. Logistic regression was used to examine associations between participant characteristics and engagement with OAT.

resultsOf 403 participants (mean age 44; 65% male), 77% were currently receiving OAT (60% methadone, 11% sublingual buprenorphine and 27% long-acting injectable buprenorphine), 13% previously and 9% never. Differences between OAT status groups included those currently receiving OAT reporting lower rates of homelessness and extra-medical opioid use, and greater group therapy engagement and past-year receipt of naloxone kits compared to those previously and never receiving OAT. Past-month daily injecting drug use was higher among those previously and never receiving OAT; those previously receiving OAT also reported the highest rate of past-year supervised injecting facility use and overdoses in the past 6 months. DISCUSSION AND

conclusionsThose not receiving OAT reported greater social instability, recent injecting drug use and drug-related harm. Variation in harm reduction service use suggests tailored strategies are needed to reach those outside OAT. These findings highlight the need for integrated, diverse strategies to address dependence-related harms.

Indexed as

Analgesics, OpioidHarm ReductionOpiate Substitution TreatmentOpioid-Related DisordersAdultBuprenorphineFemaleHumansMaleMethadoneMiddle AgedNew South WalesSurveys and QuestionnairesAnalgesics, OpioidBuprenorphineMethadoneincarcerationmental disordersopioid agonist treatmentopioid dependence

Identifiers

PMID41848413
PMCPMC12998408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.