Evidence map›Paper›PMID 41848387›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Amyloid-β 1-42 fibrils regulate SH-SY5Y cell adhesion in a delayed manner.

Urša Pečar Fonović, Slavko Kralj, Janko Kos

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Urša Pečar FonovićFaculty of Pharmacy, University of Ljubljana, Aškerčeva, Slovenia.ORCID 0009-0008-7596-9509
Slavko KraljFaculty of Pharmacy, University of Ljubljana, Aškerčeva, Slovenia.ORCID 0000-0002-0771-3818
Janko KosFaculty of Pharmacy, University of Ljubljana, Aškerčeva, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid-β peptide (Aβ), a hallmark peptide in the pathology of Alzheimer's disease, together with the amyloid-β protein precursor, is increasingly associated with the disruption of cell adhesion. In addition to its well-characterized role in plaque formation and synaptic dysfunction, Aβ interacts with various adhesion molecules and extracellular matrix components, thereby impairing neuronal connectivity and integrity. We have shown that pretreatment of SH-SY5Y cells with Aβ

Indexed as

AmyloidAmyloid beta-PeptidesCell AdhesionPeptide FragmentsCell Line, TumorHumansTime FactorsAmyloidAmyloid beta-Peptidesamyloid beta-protein (1-42)Peptide FragmentsAlzheimer's diseaseamyloid-β fibrilscell adhesionSH-SY5Y

Identifiers

PMID41848387
PMCPMC13110308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.