In one paragraphObservational study in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
31 authors.
Pier Pasquale LeoneDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0000-0002-0561-4760 Damiano RegazzoliCardio Center IRCCS Humanitas Research Hospital Rozzano, Milan Italy.
Matteo SturlaDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0000-0002-1096-962X Antonella MillinDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0009-0008-7184-4872 Matteo PagnesiInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health University of Brescia Brescia Italy.ORCID 0000-0002-9298-7871 Juan TorradoDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0000-0002-6527-4219 Francesco CannataDepartment of Perioperative Cardiology and Cardiovascular Imaging Centro Cardiologico Monzino IRCCS Milan Italy.
Rui Campante TelesHospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide and Comprehensive Health Research Center (CHRC) Nova Medical School Lisbon Portugal.ORCID 0000-0002-7952-6878 Marianna AdamoInstitute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health University of Brescia Brescia Italy.ORCID 0000-0002-3855-1815 Maurizio TaramassoHerzZentrum Hirslanden Zurich Switzerland and University of Nicosia Cyprus.
Federico De MarcoUnità Operativa di Cardiologia Interventistica Valvolare e Strutturale Centro Cardiologico Monzino Milan Italy.ORCID 0000-0003-3554-6938 Francesco SaiaCardiology Unit, St. Orsola Hospital IRCCS Azienda Ospedaliero-Universitaria di Bologna Italy.ORCID 0000-0001-9969-2649 Andrea BuonoInterventional Cardiology Unit, Cardiovascular Department Fondazione Poliambulanza Istituto Ospedaliero Brescia Italy.ORCID 0000-0001-5767-7416 Alfonso IelasiDivision of Cardiology, Department of Medicine University of Verona Italy.
Diego MaffeoInterventional Cardiology Unit, Cardiovascular Department Fondazione Poliambulanza Istituto Ospedaliero Brescia Italy.ORCID 0000-0002-6320-2959 Francesco BedogniDepartment of Cardiology IRCCS Policlinico San Donato, San Donato Milanese Milan Italy.
Nicolas Van MieghemDepartment of Cardiology Thoraxcenter, Erasmus Medical Center Rotterdam the Netherlands.ORCID 0000-0002-2732-1205 Giuliano CostaU.O.C. Cardiologia, Centro Alte Specialità e Trapianti, P.O.G. Rodolico, A.O.U. Policlinico-V. Emanuele Università di Catania Catania Italy.ORCID 0000-0003-3770-8988 Manaf AssafinDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.
Edwin C HoDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0000-0002-5126-6314 Bernhard ReimersCardio Center IRCCS Humanitas Research Hospital Rozzano, Milan Italy.
Howard C HerrmannCardiovascular Division, Hospital of the University of Pennsylvania Philadelphia PA USA.ORCID 0000-0003-3322-9568 Azeem LatibDivision of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine Bronx NY USA.ORCID 0000-0001-9035-343X Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundAmong patients treated for severe aortic stenosis, a small aortic annulus could have a different impact on outcomes according to body size. We aimed to compare forward-flow hemodynamics and clinical outcomes after transcatheter aortic valve replacement in patients with small annuli according to aortic annular area (AAA) index, defined as computed tomography-derived AAA divided by body surface area.
methodsThe TAVI-SMALL 2 (International Multicenter Registry to Evaluate the Performance of Self-Expandable Valves in Small Aortic Annuli 2) observational, retrospective, international cohort study enrolled patients with severe aortic stenosis and small annuli in 16 high-volume centers between 2011 and 2020. Analyses comparing patients with low (ie, ≤2 cm
resultsA total of 1256 patients were included in the analysis. In the 1:1 propensity score-matched population (n=688), the primary predischarge forward-flow composite end point occurred in 48 patients (7.5%) overall and was more common in low versus high AAA index (9.7% versus 5.3%,
conclusionsAmong patients with small aortic annuli undergoing transcatheter aortic valve replacement, the novel AAA index further identifies patients at increased risk of predischarge suboptimal forward-flow hemodynamics. No difference in clinical efficacy at 1-year follow-up was observed according to the AAA index.
Indexed as
Aortic ValveAortic Valve StenosisHemodynamicsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHeart Valve ProsthesisHumansMaleProsthesis DesignRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness Indexaortic annular area indexbody surface areaprosthesis–patient mismatchsmall annuliTAVR
Identifiers
PMID41848051
PMCPMC13279231
What OpenQuestion holds
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