Evidence map›Paper›PMID 41847971›Full record

ArticleHuman brain mapping2026

Sub-Networks of the Brain R

Melissa Lamar, Maude Wagner, Sue E Leurgans, Wenqing Fan, Shengwei Zhang, Victoria Poole, Lisa L Barnes, Mayra L Estrella, Julie A Schneider, Konstantinos Arfanakis

Abstract read
In one paragraph

Article in Human brain mapping, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melissa LamarRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Maude WagnerRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Wenqing FanRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Shengwei ZhangRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Victoria PooleRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Mayra L EstrellaDepartment of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Julie A SchneiderRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Konstantinos ArfanakisRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Rush Alzheimer's Disease Research CenterP30AG072975 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Lisa L Barnes, Julie A. Schneider · 2021 to 2026
$24.7M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
MRI markers of brain aging and risk factors for cognitive decline in older African AmericansR01AG056405 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2018 to 2023
$3.6M
Multimodal MRI biomarkers of small vessel disease for older persons with and without dementia.UH3NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2018 to 2020
$3.5M
Favorable cardiovascular health, connectome integrity, and ADRD clinical outcomes and pathologic underpinnings in a diverse cohort.R01AG076143 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2022 to 2025
$2.7M
Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementiaUF1NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2021 to 2021
$2.5M
Protective Factors of Cognitive Aging among Latinos in the 50 States and Puerto RicoK01AG075353 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Mayra Lorell Estrella · 2022 to 2026
$593k
NIA NIH HHS K01 AG075353NIA NIH HHS P30 AG010161NIA NIH HHS P30AG072975NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG056405NIA NIH HHS R01 AG062711NIA NIH HHS R01 AG076143NINDS NIH HHS UF1NS100599NINDS NIH HHS UH3 NS100599
6 · The paper itself

Abstract

Neuroimaging the structural connectome provides a window into the aging brain; however, few studies address the complexities of mapping late-life structural connectivity. We defined white matter connections via a structural connectivity-based atlas and extracted transverse relaxation rates (R

Indexed as

AgingBrainCognitionConnectomeMotor ActivityNerve NetWhite MatterAgedAged, 80 and overFemaleHumansMagnetic Resonance ImagingMalebrain agingcognitionmotor functionR2structural connectometransverse relaxation rates

Identifiers

PMID41847971
PMCPMC13093539

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.