Evidence map›Paper›PMID 41847966›Full record

SynthesisBipolar disorders2026

Comorbid Schizophrenia and Psychotic Symptoms in Patients With Bipolar Disorder: A Meta-Analysis of the Global Literature.

Wen Shao, Kangning Shao, Richard P Bentall

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Bipolar disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wen ShaoDepartment of Psychology, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8716-5312
Kangning ShaoThe Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Richard P BentallDepartment of Psychology, University of Sheffield, Sheffield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe boundary between bipolar disorder and schizophrenia has long been blurred by the shared psychopathology, genetic risk, and social factors. This study aims to examine the prevalence of psychosis and psychotic symptoms in bipolar patients.

methodKey words 'bipolar', 'psychosis', 'schizophrenia', and the variants were searched in titles and abstracts using Medline, Psych INFO and Web of Science and forward and backward citation searches were conducted; effects were computed using single proportion analysis with double arcsine transformation.

resultsThe final analysis comprised 285 studies. The comorbidity of schizophrenia diagnoses in bipolar patients was low (8%). However, more broadly defined mood incongruent psychosis was quite prevalent (47%). Similarly, psychotic symptoms were common in bipolar patients, specifically those with a type I diagnosis or manic episode; delusions were more common than hallucinations and thought disorders.

conclusionsSignificant overlap in phenomenology and psychopathology was observed between bipolar disorder and schizophrenia in this review. Future research should focus on comparing patients with similar symptoms and exploring the shared processes that contribute to these symptoms.

Indexed as

Bipolar DisorderPsychotic DisordersSchizophreniaComorbidityHumansbipolarprevalencepsychosisschizophrenia

Identifiers

PMID41847966
PMCPMC12997143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.