Evidence map›Paper›PMID 41847961›Full record

ArticleOrthodontics & craniofacial research2026

Three-Dimensional Facial Soft Tissue Changes Following Two Versus Four Miniscrew-Anchored Rapid Maxillary Expansion in Late Adolescence: A Secondary Data Analysis From a Randomised Clinical Trial.

Ivan Silva, Felicia Miranda, João Gabriel Rando Poiani, José Carlos da Cunha Bastos, Beatriz Quevedo, Lucia Cevidanes, Daniela Garib

Abstract read
In one paragraph

Article in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ivan SilvaDepartment of Orthodontics Bauru Dental School, University of São Paulo, Bauru, Brazil.ORCID https://orcid.org/0000-0002-2157-0104
Felicia MirandaDepartment of Orthodontics Bauru Dental School, University of São Paulo, Bauru, Brazil.
João Gabriel Rando PoianiDepartment of Orthodontics Bauru Dental School, University of São Paulo, Bauru, Brazil.
José Carlos da Cunha BastosHospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil.
Beatriz QuevedoDepartment of Orthodontics Bauru Dental School, University of São Paulo, Bauru, Brazil.
Lucia CevidanesDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, Chapel Hill, USA.
Daniela GaribDepartment of Orthodontics Bauru Dental School, University of São Paulo, Bauru, Brazil.ORCID https://orcid.org/0000-0002-2449-1620

Funding

Quantification of 3D Bony Changes in Temporomandibular Joint OsteoarthritisR01DE024450 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Lucia H Cevidanes · 2013 to 2026
$5.5M
Fundação de Amparo à Pesquisa do Estado de São Paulo #2023/08038-9Fundação de Amparo à Pesquisa do Estado de São Paulo #2024/17770-8NIDCR NIH HHS R01 DE024450
6 · The paper itself

Abstract

objectiveTo assess the facial soft tissue modifications following rapid maxillary expansion (RME) with Hybrid Hyrax (HH) and MARPE during late adolescence through 3D stereophotogrammetry.

methodsTwenty-two patients with maxillary constrictions and posterior crossbites were randomly allocated into two groups. The HH group (n = 11; mean age 16.7 ± 1.85 years) received an expander anchored with two palatal miniscrews, while the MARPE group (n = 11; mean age 16.2 ± 1.39 years) received an expander with four miniscrews. The expander screws were activated one-quarter turn twice a day for 14 days. 3D facial images were captured at baseline (T1), immediately after the active phase of the expansion (T2) and 6 months post-retention (T3). 3D images were processed using the Quantificare LifeViz Mini App software (Quantificare S.A, France) to achieve 3D measurements. Data analysis was performed blindly, on an intention-to-treat approach. Changes were analysed using two-way ANOVA with repeated measures (p < 0.05).

resultsBoth groups showed similar patterns of soft tissue changes. Nasal base width increased significantly from T1 to T2 in both groups (HH: 1.5 mm; MARPE: 1.9 mm), followed by a slight decrease at T3. Inter-commissural distance increased (HH: 1.6 mm; MARPE: 2.4 mm) and partially relapsed after expansion. A significant increase in inter-canthal distance was observed in the MARPE group (1.0 mm). Bizygomatic width remained stable after expansion in both groups. Upper and lower facial heights showed increases after expansion (HH: 0.5 mm, MARPE: 1.4 mm; HH: 0.3 mm, MARPE: 0.9 mm, respectively), with no difference between groups.

conclusionRME anchored on two and four palatal miniscrews in late adolescents produced similar increases in the facial soft tissue immediately after expansion.

trial registrationReBEC UTN code: U1111-1296-4040.

Indexed as

image three‐dimensionalmaxillary expansionorthodontic anchorage procedureorthodontic appliance

Identifiers

PMID41847961
PMCPMC13580381

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.