ArticleACS medicinal chemistry letters2026
Development and Validation of a Multicyclic Peptide Targeting PD-L1 for Radiotheranostics.
Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
Abstract
The advent of immune checkpoint blockade therapy, exemplified by inhibitors targeting programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) axis, has revolutionized the landscape of clinical oncology. Despite its remarkable success, therapeutic benefits remain limited to a subset of patients, highlighting the urgent need for more accurate methods of patient stratification. Conventional techniques for assessing PD-L1 expression, such as immunohistochemistry, provide static and localized information but lack the ability to capture whole-body distribution or temporal dynamics. In contrast, positron emission tomography (PET) offers a noninvasive approach for visualizing PD-L1 expression and disease burden
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