Evidence map›Paper›PMID 41847620›Full record

ArticleiScience2026

Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.

Nanami Senoo, Macie S Sheridan, Yvonne Wohlfarter, Mackenzie T Primrose, Emmanouil Tampakakis, Markus A Keller, Steven M Claypool

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nanami SenooDepartment of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Macie S SheridanDepartment of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Yvonne WohlfarterInstitute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1/1.OG, Innsbruck, Tyrol 6020, Austria.
Mackenzie T PrimroseDepartment of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Emmanouil TampakakisDepartment of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA.
Markus A KellerInstitute of Human Genetics, Medical University of Innsbruck, Peter-Mayr-Str. 1/1.OG, Innsbruck, Tyrol 6020, Austria.
Steven M ClaypoolDepartment of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Funding

An intimate and multifaceted partnership: cardiolipin and the mitochondrial ADP/ATP carrierR01HL165729 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Steven Michael Claypool · 2023 to 2026
$2.1M
Molecular basis to regulate the cardiac-specific form of mitochondrial phospholipid cardiolipinK99HL168075 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SENOO, NANAMI · 2024 to 2025
$215k
NHLBI NIH HHS K99 HL168075NHLBI NIH HHS R01 HL165729
6 · The paper itself

Abstract

Barth syndrome, a rare X-linked genetic disorder, features early-onset cardiomyopathy. The causal gene,

Indexed as

Biological sciencesCell biologyMolecular biology

Identifiers

PMID41847620
PMCPMC12989855

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.