ArticleiScience2026
Oral microbiome diversity shapes the association between leisure-time physical activity and cognitive function among older adults.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Perceived physical literacy, self-reported physical activity, and sports video gaming among university students: a cross-sectional study.Journal of exercise science and fitness · 2026Article
- Dual-task versus single-task walking within an Otago Exercise Program for older adults with dementia: A 24-week cluster randomized controlled trial.Journal of exercise science and fitness · 2026Article
- Physical Activity Prescription in Saudi Healthcare: Investigating Healthcare Practitioners' and Community's Knowledge, Attitude, and Practice.Journal of multidisciplinary healthcare · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regular leisure-time physical activity and the composition of the oral microbiome may influence late-life cognition, but their combined effects are unclear. We studied 575 US adults aged 60-69 years from a nationally representative survey with oral microbiome sequencing, self-reported leisure-time physical activity, and four standard cognitive tests of memory, verbal fluency, and processing speed. Higher weekly physical activity and meeting current guideline levels were associated with better memory and processing speed scores after multivariable adjustment. Greater oral microbiome diversity, including higher richness and evenness, was also related to better processing speed. Among participants who met activity guidelines, those with intermediate to high Shannon diversity and a specific community composition profile showed the most favorable verbal fluency and processing speed. These findings suggest that maintaining both regular physical activity and a diverse oral microbiome may jointly support cognitive function in later life and promote healthy aging.
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Registered trials
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