ArticleRSC advances2026
A novel room-temperature CQD fluorescent nanosensor for the first derivatization-free spectrofluorimetric determination of dalfampridine: application to biological fluids and content uniformity testing.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents a novel approach for producing luminescent carbon quantum dots (CQDs) at room temperature (RT) utilizing hydroquinone and monosodium glutamate (MSG) as precursors through a simple reaction with no energy consumption. The produced RT-CQDs have a tiny diameter of 3.6 nm and a high quantum yield of 38.05%. Many spectroscopic and microscopic techniques, including HRTEM, zeta potential, EDX, FT-IR, UV/Visible, and fluorescence spectroscopy were utilized to characterize the produced RT-CQDs. After excitation at 290 nm, the RT-CQDs showed a high emission at 327 nm. The produced RT-CQDs' fluorescence signal was quantitatively decreased by dalfampridine (DFP), enabling their use as a sensitive fluorescent nanosensor to measure DFP in different matrices without the need for any pre-derivatization steps or a large volume of organic solvents, for the first time. The developed method showed a correlation coefficient of 0.9998, wide linearity range of 0.02-14.0 µg mL
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Registered trials
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