Evidence map›Paper›PMID 41847531›Full record

ArticleRSC advances2026

Mannich reaction with organozinc reagents in continuous flow: experimental and computational studies.

Lucas Fraile-González, Ángel Sánchez-González, Laura F Peña, Enol López

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucas Fraile-GonzálezDepartment of Organic Chemistry, School of Engineering (EII) University of Valladolid (UVa). Dr Mergelina 47002 Valladolid Spain enol.lopez@uva.es.ORCID https://orcid.org/0009-0000-3402-6768
Ángel Sánchez-GonzálezDepartment of Organic Chemistry, School of Engineering (EII) University of Valladolid (UVa). Dr Mergelina 47002 Valladolid Spain enol.lopez@uva.es.
Laura F PeñaFaculty of Pharmacy, University of Castilla-La Mancha. Calle Almansa 14 - Edif. Bioincubadora 02008 Albacete Spain.ORCID https://orcid.org/0000-0002-4444-0062
Enol LópezDepartment of Organic Chemistry, School of Engineering (EII) University of Valladolid (UVa). Dr Mergelina 47002 Valladolid Spain enol.lopez@uva.es.ORCID https://orcid.org/0000-0002-1337-0604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a fully continuous flow version of a Mannich reaction using organozinc reagents. These organometallics were generated

Identifiers

PMID41847531
PMCPMC12990320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.