Evidence map›Paper›PMID 41847457›Full record

ReviewFrontiers in endocrinology2026

Reflections on prevention and treatment of post-thyroidectomy hypoparathyroidism: current management approaches and future prospects.

Jia Li, Zilai Hu, Zhiyuan Ma, Guoli Feng, Lanhai Zhang, Suansuan Zhu, Jinyan Hu, Wei Han, Taolang Li

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jia LiDepartment of Hepatobiliary Pancreatic and Thyroid Surgery, Department of General Surgery, People's Hospital of Zunyi City Bozhou District, Zunyi, China.
Zilai HuDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhiyuan MaDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Guoli FengDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Lanhai ZhangDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Suansuan ZhuDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Jinyan HuDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Wei HanDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Taolang LiDepartment of Thyroid and Breast Surgery, Department of General Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative hypoparathyroidism (hypoPT) is one of the predominant and severe complications of thyroid surgery. This condition manifests as suboptimal circulatory levels of parathyroid hormone (PTH), engendering multifaceted systemic perturbations. This comprehensive review elucidates the underlying pathophysiological mechanisms and clinical presentations associated with hypoparathyroidism. Moreover, methodologies for the precise recognition and preservation (naked eye, near-infrared autofluorescence, indocyanine green, carbon nanoparticles, and mitoxantrone hydrochloride) of the parathyroid gland during thyroid surgery have been explored, along with recent therapeutic innovations (palopegteriparatide and parathyroid organoids). Finally, this review prospects and interventions via organoids are contemplated. The aim of the literature is to recapitulate the knowledge and the gaps in this field, increasing awareness of postoperative hypoparathyroidism, and improve the prognosis for patients afflicted with hypoparathyroidism.

Indexed as

HypoparathyroidismPostoperative ComplicationsThyroidectomyHumansParathyroid Glandsmanagementparathyroid organoidpostoperative hypoparathyroidismpostsurgical hypocalcemiarecombinant PTHthyroid surgerytreatment

Identifiers

PMID41847457
PMCPMC12990180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.