Evidence map›Paper›PMID 41847450›Full record

ArticleFrontiers in endocrinology2026

Sex- and stage-dependent expression of gonadal soma-derived factor paralogues reveals functional and evolutionary divergence in European sea bass (

Alessia Mascoli, Cinta Zapater, Joan Pizarro-Gomez, Ana Gómez

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In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessia MascoliDepartment of Fish Physiology and Biotechnology, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas (CSIC), Torre la Sal, Castellón, Spain.
Cinta ZapaterDepartment of Fish Physiology and Biotechnology, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas (CSIC), Torre la Sal, Castellón, Spain.
Joan Pizarro-GomezDepartment of Fish Physiology and Biotechnology, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas (CSIC), Torre la Sal, Castellón, Spain.
Ana GómezDepartment of Fish Physiology and Biotechnology, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas (CSIC), Torre la Sal, Castellón, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The gonadal soma-derived factor (Gsdf) is a member of the Transforming Growth Factor-β (TGF-β) superfamily, with key roles in teleost reproduction, particularly in males. Previously considered teleost-specific, its presence in non-teleostvertebrates indicates a more ancient evolutionary origin. It is still classified as an orphan ligand with uncharacterized signaling pathways, and its evolution, regulatory mechanisms, and functional divergence remain unclear. Methods: The roesent work provides a comprehensive characterization of two Results: Phylogenetic reconstruction of 31 species revealed that Conclusions: These results support the subfunctionalization of

Indexed as

BassEvolution, MolecularFish ProteinsTransforming Growth Factor betaAnimalsFemaleGene DuplicationGene Expression Regulation, DevelopmentalMalePhylogenySexual MaturationFish ProteinsTransforming Growth Factor betaevolutiongametogenesisgene duplicationgonadal factorsreproductionteleost

Identifiers

PMID41847450
PMCPMC12989411

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.