ArticleFrontiers in cellular and infection microbiology2026
Interkingdom signaling elicited by bacterial extracellular vesicles in human cystic fibrosis airway epithelium and neutrophils.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rationale: Defects in epithelial host defense and dysfunctional neutrophilic inflammation in the presence of sustained bacterial infection underpin chronic lung disease in cystic fibrosis (CF). Deciphering mechanisms on how bacteria interact with the host to establish chronic infection is critical for disease control in people with CF (pwCF). Objective: We sought to investigate the co-existence of microbial and host extracellular vesicles (EVs) in CF airway fluids and evaluate if bacterial EVs from Methods: EVs from sputum and bronchoalveolar lavage fluid from pwCF ( Results: We observed the co-existence of bacterial and host EVs in airway fluid from pwCF. Functionally, exposure to EVs from wild-type Conclusion: This proof-of-concept study suggests host-bacterial interplay via EVs in CF airways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.