ArticleInfection and drug resistance2026
Prevalence and Determinants of Multi-Drug Resistance Bacterial Infection Among Burn Patients in a Tertiary Care Center in Nepal.
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A 16-Year-Old Male Patient With Severe Electrical Burns With Chronic and Recurrent Hospital-Acquired Opportunistic Infection With Carbapenem-Resistant Acinetobacter baumannii.The American journal of case reports · 2026Article
- Infections in Burn Patients: Pathophysiology, Prevention, and Contemporary Therapeutic Strategies in the Era of Antimicrobial Resistance.Infectious diseases and therapy · 2026Review
- Epidemiology, pathogen spectrum, and antimicrobial resistance of infections in burn patients stratified by total body surface area: a bicenter study with evaluation of targeted next-generation sequencing.Frontiers in microbiology · 2026Article
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Authors and funding
7 authors.
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Abstract
Purpose: The emergence of multidrug-resistant organisms (MDROs) in burn patients poses a significant threat to patient outcomes and healthcare systems, especially in resource-limited settings. Burn injuries compromise the skin barrier and often require invasive interventions, increasing the risk of infection and antimicrobial resistance. This study aimed to determine the prevalence of multi-drug resistance (MDR) and identify the associated risk factors. Patient and Methods: A retrospective study was conducted among burn patients admitted to Nepal Cleft and Burn Center, Kathmandu, from January to December 2023. All culture-positive isolates were assessed to determine the prevalence of MDR and distribution of common pathogens. Sociodemographic and clinical data were evaluated using multivariate logistic regression to identify predictors of MDRO infection. Results: Among 535 burn patients, 348 had positive cultures. The prevalence of resistant organisms was 56.82%, comprising MDR (n = 155), Extensively Drug-Resistant (XDR) (n = 147), and Pan-drug Resistant (PDR) (n = 2). The most common Gram-negative isolates were Conclusion: MDRO infections are highly prevalent (56.82%) in burn patients. ICU stay and use of invasive devices are key risk factors. These findings underscore the importance of antimicrobial stewardship, stringent infection control measures, and routine surveillance for antimicrobial resistance in burn units.
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