Evidence map›Paper›PMID 41847354›Full record

ArticleFrontiers in veterinary science2026

Dysregulated interferon signaling and hyperinflammation upon

Yingxue Yang, Xiangyin Chen, Ziying Wang, Lili Wu, Li Du, Hongyan Gao, Si Chen, Qiaoling Chen, Fengyang Wang

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yingxue YangHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Xiangyin ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Ziying WangHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Lili WuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Li DuHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Hongyan GaoHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Si ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Qiaoling ChenHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Fengyang WangHainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, Animal Genetic Engineering Key Laboratory of Haikou, College of Tropical Agriculture and Forestry, Hainan University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Fc gamma binding protein (FCGBP) is pivotal for mucosal immune defense against Methods: This study investigated the role of FCGBP in the immune response of goat bronchial epithelial cells against Results and discussion: The results indicated that FCGBP maintains homeostasis and provides immune protection in goat lungs. Knockdown of FCGBP in goat bronchial epithelial cells leads to impaired cellular barrier function, resulting in excessive activation of type I interferon, HIF-1, TNF, and NOD-like receptor signaling pathways following infection with

Indexed as

Fcgbpgoat bronchial epithelial cellsInflammationPasteurella multocidaRNA-Seq

Identifiers

PMID41847354
PMCPMC12989410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.