ArticleIJTLD open2026
The impact of non-TB mycobacterial co-isolation in patients with pulmonary TB.
Article in IJTLD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundPulmonary TB is diagnosed by isolating
methodsWe conducted a retrospective study of pulmonary TB patients treated at West Park Healthcare Centre between 2010 and 2020. Demographics, microbiologic data, and clinical outcomes were extracted. Patients with NTM co-isolation were compared to those with TB-alone.
resultsAmong 771 patients, 284 co-isolated NTM. These patients were older (median 58 vs. 49 years) and more often had diabetes (28.5% vs. 18.7%). They had longer time to sputum culture conversion (56 vs. 45.5 days) and were less likely to achieve sputum culture conversion (73.1% vs. 82.7%). NTM co-isolated patients had more persistent cough and sputum at treatment completion.
conclusionNTM co-isolation in TB occurs more commonly in older patients, and those with diabetes. Patients who co-isolate NTM during TB treatment are less likely to culture convert, have a longer time to culture conversion, and have more end-of-treatment symptoms.
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